How high and low testosterone affect organs differently | Peter Attia & Ted Schaeffer

Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Watch the full episode: https://youtu.be/fiVCsm4dNh0 Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode #310 - The relationship between testosterone and prostate cancer, TRT, and more with Ted Schaeffer, M.D., Ph.D. In this clip, they discuss: - The androgen receptor saturation theory, which suggests that once testosterone (T) levels in an organ reach a certain threshold, additional testosterone has minimal effect on receptor activity - How organs like the prostate and hair follicles convert T to DHT via 5α-reductase, making them more sensitive to T at lower levels - Evidence showing that increasing T from low to moderate levels (e.g., 300 to 800 ng/dL) likely has minimal effect on prostate growth or hair loss but can significantly impact muscle mass - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: https://peterattiamd.com/terms-of-use/