
Advantages of TIGR-Tas gene editing systems over CRISPR-Cas
SciShow, 20 min, 1.4M views, Jan 20, 2026
Original title: The Successor to CRISPR May Be Even More World Changing
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When Feng Zhang was in his early 30s, he used a set of genes found in bacteria called CRISPR to pioneer a new kind of gene editing tool in human cells. Today, the MIT biochemist is studying a different set of microbial genes called TIGR. And they may be the key to developing CRISPR's successor. For this SciShow Field Trips video, we traveled to Zhang's lab to learn about what may be the next generation of gene editing. Hosted by: Jaida Elcock ---------- Support us for $8/month on Patreon and keep SciShow going! https://www.patreon.com/scishow Or support us directly: https://complexly.com/support Join our SciShow email list to get the latest news and highlights: https://mailchi.mp/scishow/email ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: David Johnston, Cye Stoner, Jp Lynch, Bethany Matthews, Chris Curry, J.V. Rosenbalm, Alan Wong, Toyas Dhake, Reed Spilmann, Garrett Galloway, Friso, Lyndsay Brown, Jeremy Mattern, Jaap Westera, Matt Curls, Eric Jensen, Chris Mackey, Adam Brainard, Piya Shedden, Steve Gums, Alex Hackman, Kevin Knupp, Chris Peters, Kevin Bealer, Joseph Ruf, Jason A Saslow ---------- Looking for SciShow elsewhere on the internet? SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/ TikTok: https://www.tiktok.com/@scishow Instagram: http://instagram.com/thescishow Facebook: http://www.facebook.com/scishow Bluesky: https://bsky.app/profile/scishow.bsky.social #SciShow #science #education #learning #complexly ---------- Sources: https://docs.google.com/document/d/e/2PACX-1vQJm7Y0sBNUGaj1Y6867KxRUngr7pinUx2Ou79SNfQYFucabVssCksB2-0sCX3SUVCA8ANhcAtDG83K/pub